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beta-2 Microglobulin anticorps (AA 21-100)

B2M Reactivité: Humain WB, FACS, ELISA, IHC Hôte: Souris Monoclonal 3G5H8 unconjugated
N° du produit ABIN1724930
  • Antigène Voir toutes beta-2 Microglobulin (B2M) Anticorps
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Épitope
    • 19
    • 17
    • 15
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-100
    Reactivité
    • 209
    • 52
    • 30
    • 27
    • 10
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 123
    • 116
    • 9
    • 6
    • 2
    • 1
    Souris
    Clonalité
    • 131
    • 125
    • 1
    Monoclonal
    Conjugué
    • 113
    • 32
    • 26
    • 14
    • 13
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp beta-2 Microglobulin est non-conjugé
    Application
    • 128
    • 110
    • 75
    • 66
    • 60
    • 41
    • 40
    • 31
    • 26
    • 18
    • 17
    • 15
    • 13
    • 12
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human B2M (AA: 21-100) expressed in E. coli.
    Clone
    3G5H8
    Isotype
    IgG2a
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Bernal, Ruiz-Cabello, Concha, Paschen, Garrido: "Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." dans: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, (2012) (PubMed).

    Hermansen, Hummelshøj, Lundsgaard, Hornum, Keller, Fleckner, Fox, Poulsen, Jacobsen: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." dans: Lupus, Vol. 21, Issue 10, pp. 1098-104, (2012) (PubMed).

  • Antigène
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Autre désignation
    B2M (B2M Produits)
    Synonymes
    anticorps Ly-m11, anticorps beta2-m, anticorps beta2m, anticorps bwm, anticorps wu:fa94c05, anticorps wu:fb10a09, anticorps b2m-W01, anticorps b2m-W03, anticorps b2m-Z01, anticorps b2m-Z02, anticorps b2m-Z03, anticorps B2M, anticorps b2m, anticorps B2MG, anticorps wu:fb66f11, anticorps wu:fj01f08, anticorps zgc:64161, anticorps b-2-m, anticorps beta-2-microglobulin, anticorps beta-2 microglobulin, anticorps beta-2-microglobulin S homeolog, anticorps beta-2-microglobulin, like, anticorps B2M, anticorps B2m, anticorps b2m, anticorps b2m.S, anticorps b2ml
    Sujet
    This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. ,
    Poids moléculaire
    13.7 kDa
    ID gène
    567
    HGNC
    567
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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