GABBR2 anticorps (AA 319-483)
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- Antigène Voir toutes GABBR2 Anticorps
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
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Épitope
- AA 319-483
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GABBR2 est non-conjugé
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Application
- Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- Fonction
- GABBR2 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.
- Clone
- 5G7F7
- Isotype
- IgG2a
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- Indications d'application
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." dans: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).
: "
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GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." dans: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).
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- Antigène
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
- Autre désignation
- GABBR2 (GABBR2 Produits)
- Synonymes
- anticorps Gpr51, anticorps GABABR2, anticorps GPR51, anticorps GPRC3B, anticorps HG20, anticorps HRIHFB2099, anticorps Gb2, anticorps Gm425, anticorps GABA(B)R2, anticorps si:dkey-190l1.2, anticorps gamma-aminobutyric acid type B receptor subunit 2, anticorps gamma-aminobutyric acid (GABA) B receptor, 2, anticorps gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog, anticorps GABBR2, anticorps LOC100448699, anticorps gabbr2, anticorps Gabbr2, anticorps gabbr2.S
- Sujet
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Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Aliases: HG20, GPR51, GPRC3B, GABABR2, HRIHFB2099
- Poids moléculaire
- 105.8kDa
- ID gène
- 9568
- HGNC
- 9568
- UniProt
- O75899
- Pathways
- cAMP Metabolic Process
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