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GABBR2 anticorps (AA 319-483)

GABBR2 Reactivité: Humain IHC, ELISA, ICC Hôte: Souris Monoclonal 5G7F7 unconjugated
N° du produit ABIN1724937
  • Antigène Voir toutes GABBR2 Anticorps
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Épitope
    • 19
    • 15
    • 15
    • 15
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 319-483
    Reactivité
    • 94
    • 70
    • 64
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 110
    • 15
    Souris
    Clonalité
    • 102
    • 23
    Monoclonal
    Conjugué
    • 33
    • 10
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GABBR2 est non-conjugé
    Application
    • 111
    • 52
    • 52
    • 37
    • 31
    • 16
    • 15
    • 13
    • 12
    • 6
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Fonction
    GABBR2 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.
    Clone
    5G7F7
    Isotype
    IgG2a
  • Indications d'application

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Balasubramanian, Fam, Hall: "GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." dans: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).

  • Antigène
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Autre désignation
    GABBR2 (GABBR2 Produits)
    Synonymes
    anticorps Gpr51, anticorps GABABR2, anticorps GPR51, anticorps GPRC3B, anticorps HG20, anticorps HRIHFB2099, anticorps Gb2, anticorps Gm425, anticorps GABA(B)R2, anticorps si:dkey-190l1.2, anticorps gamma-aminobutyric acid type B receptor subunit 2, anticorps gamma-aminobutyric acid (GABA) B receptor, 2, anticorps gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog, anticorps GABBR2, anticorps LOC100448699, anticorps gabbr2, anticorps Gabbr2, anticorps gabbr2.S
    Sujet

    Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.



    Aliases: HG20, GPR51, GPRC3B, GABABR2, HRIHFB2099

    Poids moléculaire
    105.8kDa
    ID gène
    9568
    HGNC
    9568
    UniProt
    O75899
    Pathways
    cAMP Metabolic Process
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