GABBR2 anticorps (AA 319-483)

N° du produit ABIN1724937

Détail du produit anti-GABBR2 anticorps

Antigène: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Épitope: AA 319-483

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GABBR2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Fonction: GABBR2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.

Clone: 5G7F7

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-GABBR2 (ABIN1724937)

Balasubramanian, Fam, Hall: "GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." dans: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).

Détails sur GABBR2

Antigène: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Autre désignation: GABBR2 (GABBR2 Produits)

Sujet:

Description: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

Aliases: HG20, GPR51, GPRC3B, GABABR2, HRIHFB2099

Poids moléculaire: 105.8kDa

ID gène: 9568

HGNC: 9568

UniProt: O75899

Pathways: cAMP Metabolic Process