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TRF2 anticorps (AA 324-500)

TERF2 Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 3H6B4 unconjugated
N° du produit ABIN1724941
  • Antigène Voir toutes TRF2 (TERF2) Anticorps
    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 324-500
    Reactivité
    • 39
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 34
    • 4
    • 2
    Souris
    Clonalité
    • 37
    • 3
    Monoclonal
    Conjugué
    • 22
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRF2 est non-conjugé
    Application
    • 29
    • 20
    • 18
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Fonction
    TERF2 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.
    Clone
    3H6B4
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Galati, Magdinier, Colasanti, Bauwens, Pinte, Ricordy, Giraud-Panis, Pusch, Savino, Cacchione, Gilson: "TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).

    Diehl, Idowu, Kimmelshue, York, Jackson-Cook, Turner, Holt, Elmore: "Elevated TRF2 in advanced breast cancers with short telomeres." dans: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).

  • Antigène
    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
    Autre désignation
    TERF2 (TERF2 Produits)
    Synonymes
    anticorps TERF2, anticorps TRBF2, anticorps TRF2, anticorps trf2, anticorps telomeric repeat binding factor 2, anticorps telomeric repeat binding factor 2 L homeolog, anticorps TERF2, anticorps Terf2, anticorps terf2.L
    Sujet

    Description: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.


    Aliases: TRF2, TRBF2

    Poids moléculaire
    55.6kDa
    ID gène
    7014
    HGNC
    7014
    UniProt
    Q15554
    Pathways
    Cycle Cellulaire, Telomere Maintenance
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