TRF2 anticorps (AA 324-500)
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- Antigène Voir toutes TRF2 (TERF2) Anticorps
- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
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Épitope
- AA 324-500
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TRF2 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Fonction
- TERF2 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.
- Clone
- 3H6B4
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).
: "Elevated TRF2 in advanced breast cancers with short telomeres." dans: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).
: "
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TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).
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- Antigène
- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
- Autre désignation
- TERF2 (TERF2 Produits)
- Synonymes
- anticorps TERF2, anticorps TRBF2, anticorps TRF2, anticorps trf2, anticorps telomeric repeat binding factor 2, anticorps telomeric repeat binding factor 2 L homeolog, anticorps TERF2, anticorps Terf2, anticorps terf2.L
- Sujet
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Description: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Aliases: TRF2, TRBF2
- Poids moléculaire
- 55.6kDa
- ID gène
- 7014
- HGNC
- 7014
- UniProt
- Q15554
- Pathways
- Cycle Cellulaire, Telomere Maintenance
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