Axin anticorps (C-Term)
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- Antigène Voir toutes Axin (AXIN1) Anticorps
- Axin (AXIN1) (Axin 1 (AXIN1))
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Épitope
- C-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Axin est non-conjugé
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Reacts with the C-terminus part of human AXIN1
- Réactivité croisée
- Souris, Boeuf (Vache), Chien, Rat (Rattus)
- Réactivité croisée (Details)
- Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.
- Purification
- Antigen affinity purified
- Immunogène
- Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)
- Top Product
- Discover our top product AXIN1 Anticorps primaire
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- Indications d'application
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Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Minimize freezing and thawing.
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- Antigène
- Axin (AXIN1) (Axin 1 (AXIN1))
- Autre désignation
- AXIN1 (AXIN1 Produits)
- Synonymes
- anticorps AXIN1, anticorps axin, anticorps fused, anticorps xAxin, anticorps LOC100226467, anticorps AXIN, anticorps PPP1R49, anticorps AI316800, anticorps Axin, anticorps Fu, anticorps Kb, anticorps Ki, anticorps kinky, anticorps knobbly, anticorps AXIN1-RGS, anticorps wu:fi22e03, anticorps wu:fj14c08, anticorps wu:fk11b03, anticorps zgc:109872, anticorps axin 1, anticorps axin 1 S homeolog, anticorps axin 1 L homeolog, anticorps AXIN1, anticorps axin1.S, anticorps axin1.L, anticorps Axin1, anticorps axin1
- Sujet
- Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
- UniProt
- O15169
- Pathways
- Signalisation WNT, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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