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Neuroligin 1 anticorps (AA 718-843) (Biotin)

NLGN1 Reactivité: Rat WB, IHC, ICC, IF Hôte: Souris Monoclonal S97A-31 Biotin
N° du produit ABIN1741316
  • Antigène Voir toutes Neuroligin 1 (NLGN1) Anticorps
    Neuroligin 1 (NLGN1)
    Épitope
    • 19
    • 16
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 718-843
    Reactivité
    • 40
    • 39
    • 24
    • 1
    Rat
    Hôte
    • 36
    • 25
    • 1
    Souris
    Clonalité
    • 40
    • 22
    Monoclonal
    Conjugué
    • 20
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Neuroligin 1 est conjugé à/à la Biotin
    Application
    • 50
    • 25
    • 22
    • 14
    • 12
    • 11
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects ~120 kDa. Does not cross-react with other Neuroligins.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 718-843 (cytoplasmic C-terminus) of rat Neuroligin-1. Mouse: 99% identity (125/126 amino acids identical). Human: 99% identity (125/126 amino acids identical) >40% identity with Neuroligin-2 and -3.
    Clone
    S97A-31
    Isotype
    IgG1
    Top Product
    Discover our top product NLGN1 Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    2 μg/ml of ABIN1741316 was sufficient for detection of Neuroligin-1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    Neuroligin 1 (NLGN1)
    Autre désignation
    Neuroligin 1 (NLGN1 Produits)
    Synonymes
    anticorps NLGN1, anticorps Nlgn1, anticorps GB18720, anticorps nlgn1, anticorps NL1, anticorps 6330415N05Rik, anticorps BB179718, anticorps mKIAA1070, anticorps neuroligin-1, anticorps neuroligin 1, anticorps NLGN1, anticorps LOC659779, anticorps LOC724358, anticorps nlgn1, anticorps Nlgn1
    Sujet
    Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.
    ID gène
    116647
    UniProt
    Q62765
    Pathways
    Synaptic Membrane, Synaptic Vesicle Exocytosis
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