QKI anticorps (AA 1-341) (APC)

N° du produit ABIN1741387

Détail du produit anti-QKI anticorps (APC)

Antigène: QKI (Protein Quaking (QKI))

Épitope: AA 1-341

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp QKI est conjugé à/à la APC

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Detects ~36-38 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical). Rat: 99% identity (339/341 amino acids identical) >90% identity with QKI-6, QKI-7 and QKI-7b.

Clone: S147-6

Isotype: IgG2b

Information d'application

Indications d'application:

• WB (1:1000)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN1741387 was sufficient for detection of Pan-QKI in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur QKI

Antigène: QKI (Protein Quaking (QKI))

Autre désignation: QKI (QKI Produits)

Synonymes: anticorps Hqk, anticorps QK, anticorps QK1, anticorps QK3, anticorps hqkI, anticorps 1110003F05Rik, anticorps 1500005P18, anticorps QkI, anticorps l(17)-1Wis, anticorps l17Wis1, anticorps Qki, anticorps CQKI, anticorps QKI-5, anticorps PqkI, anticorps BqkI, anticorps qk, anticorps qk1, anticorps quaking, anticorps Xqua, anticorps qki, anticorps EQKI, anticorps EqkI, anticorps QKI, KH domain containing RNA binding, anticorps quaking, anticorps QKI, KH domain containing, RNA binding S homeolog, anticorps QKI, KH domain containing, RNA binding L homeolog, anticorps QKI, anticorps Qk, anticorps qki.S, anticorps qki.L, anticorps Qki

Sujet: QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.

ID gène: 9444

UniProt: Q96PU8