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Neuroligin 3 anticorps (AA 730-848)

NLGN3 Reactivité: Rat WB, IHC, ICC, IF Hôte: Souris Monoclonal S110-29 unconjugated
N° du produit ABIN1741449
  • Antigène Voir toutes Neuroligin 3 (NLGN3) Anticorps
    Neuroligin 3 (NLGN3)
    Épitope
    • 19
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 730-848
    Reactivité
    • 35
    • 33
    • 27
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 38
    • 26
    • 1
    • 1
    Souris
    Clonalité
    • 43
    • 23
    Monoclonal
    Conjugué
    • 25
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Neuroligin 3 est non-conjugé
    Application
    • 38
    • 22
    • 22
    • 13
    • 13
    • 11
    • 11
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects ~110 kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.
    Clone
    S110-29
    Isotype
    IgG1
  • Indications d'application
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN1741449 was sufficient for detection of Neuroligin 3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C
  • Antigène
    Neuroligin 3 (NLGN3)
    Autre désignation
    Neuroligin 3 (NLGN3 Produits)
    Synonymes
    anticorps Nlgn3, anticorps GB18290, anticorps hnl3, anticorps NLGN3, anticorps CCE-L1, anticorps NV16744, anticorps Nv1604741, anticorps HNL3, anticorps A230085M13Rik, anticorps NL3, anticorps neuroligin 3, anticorps neuroligin 3 S homeolog, anticorps NLG-3, anticorps nlgn3.S, anticorps NLGN3, anticorps LOC659852, anticorps LOC100121155, anticorps nlgn3, anticorps Nlgn3
    Sujet
    Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.
    ID gène
    171297
    UniProt
    Q62889
    Pathways
    Synaptic Membrane
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