RAB3A anticorps (AA 2-14)

N° du produit ABIN1742211

Détail du produit anti-RAB3A anticorps

Antigène: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Épitope: AA 2-14

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Boeuf (Vache), Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB3A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Specificité: Specific for Rab 3a.

Purification: antiserum

Immunogène: Synthetic peptide ASATDSRYGQKES (aa 2-14 in rat Rab 3a) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Information d'application

Indications d'application: WB: 1 : 1000 (AP staining)
ICC: 1 : 1000

Commentaires:

ELISA: Suitable as detector antibody for sandwich-ELISA as capture antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS

Conseil sur la manipulation: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Stock: 4 °C/-20 °C

Stockage commentaire: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

Références pour anticorps anti-RAB3A (ABIN1742211)

Vasileva, Horstmann, Geumann, Gitler, Kuner: "Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission." dans: The European journal of neuroscience, Vol. 36, Issue 8, pp. 3005-20, (2012) (PubMed).

Rastaldi, Armelloni, Berra, Li, Pesaresi, Poczewski, Langer, Kerjaschki, Henger, Blattner, Kretzler, Wanke, DAmico: "Glomerular podocytes possess the synaptic vesicle molecule Rab3A and its specific effector rabphilin-3a." dans: The American journal of pathology, Vol. 163, Issue 3, pp. 889-99, (2003) (PubMed).

Schlüter, Khvotchev, Jahn, Südhof: "Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion." dans: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40919-29, (2002) (PubMed).

Von Kriegstein, Schmitz, Link, Südhof: "Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses." dans: The European journal of neuroscience, Vol. 11, Issue 4, pp. 1335-48, (1999) (PubMed).

Détails sur RAB3A

Antigène: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Autre désignation: Rab 3a (RAB3A Produits)

Synonymes: anticorps RAB3, anticorps rab3a, anticorps zgc:92276, anticorps RAB3A, anticorps rab-3a, anticorps si:ch211-255d18.4, anticorps zgc:112516, anticorps RAB3A, member RAS oncogene family, anticorps RAB3A, member RAS oncogene family, a, anticorps RAB3A, member RAS oncogene family L homeolog, anticorps RAB3A, member RAS oncogene family, b, anticorps RAB3A, anticorps Rab3a, anticorps rab3aa, anticorps rab3a.L, anticorps rab3a, anticorps rab3ab

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport