Rab3c anticorps (AA 154-227)

N° du produit ABIN1742212

Détail du produit anti-Rab3c anticorps

Antigène: Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))

Épitope: AA 154-227

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Rab3c est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificité: Specific for Rab 3c.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogène: Recombinant protein of human Rab 3c (aa 154-227).

Information d'application

Indications d'application: WB: 1 : 1000 (AP staining)
ICC: 1 : 500
IHC: not tested yet

Commentaires:

This antibody has been affinity purified with a peptide consisting only of the Rab 3c specific epitope NTRLKETPPPPQPN (aa 211 - 224) of the human protein.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Conseil sur la manipulation: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Stock: -20 °C

Stockage commentaire: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

Références pour anticorps anti-Rab3c (ABIN1742212)

Nishioka, Tooi, Isobe, Nakatsuji, Aiba: "BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models." dans: Scientific reports, Vol. 6, pp. 33427, (2016) (PubMed).

Pavlos, Grønborg, Riedel, Chua, Boyken, Kloepper, Urlaub, Rizzoli, Jahn: "Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 40, pp. 13441-53, (2010) (PubMed).

Cai, Reim, Varoqueaux, Tapechum, Hill, Sørensen, Brose, Chow: "Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 49, pp. 19538-43, (2008) (PubMed).

Détails sur Rab3c

Antigène: Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))

Autre désignation: Rab 3c (Rab3c Produits)

Synonymes: anticorps 2700062I01Rik, anticorps 3110015B08Rik, anticorps 3110037E15Rik, anticorps AI850886, anticorps rab3d, anticorps MGC130815, anticorps zgc:92916, anticorps RAB3C, anticorps RAB3C, member RAS oncogene family, anticorps RAB3D, member RAS oncogene family L homeolog, anticorps Rab3c, anticorps RAB3C, anticorps rab3d.L, anticorps rab3c