SNAPIN anticorps (C-Term)

N° du produit ABIN1742322

Détail du produit anti-SNAPIN anticorps

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Épitope: AA 117-136, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAPIN est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for snapin.

Purification: antiserum

Immunogène: Synthetic peptide TARRRAMLDSGVYPPGSPSK (aa 117-136 in rat) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Information d'application

Indications d'application: WB: 1 : 100 - 1 : 5000 (AP staining)
IP: not recommended
ICC: not tested yet
IHC: not recommended

Commentaires:

Since snapin is present in very low concentrations long exposure time is recommended.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS

Conseil sur la manipulation: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Stock: 4 °C/-20 °C

Stockage commentaire: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

Références pour anticorps anti-SNAPIN (ABIN1742322)

Zhou, Cai, Xie, Sheng: "Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons." dans: Cell reports, Vol. 2, Issue 1, pp. 42-51, (2012) (PubMed).

Zhang, Wada, Yasuhara, Iseda, Eguchi, Fukui, Yang, Yamagata, Hiesberger, Igarashi, Zhang, Wang, Akagi, Kanwar, Makino: "The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells." dans: PLoS ONE, Vol. 2, Issue 5, pp. e414, (2007) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." dans: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Vites, Rhee, Schwarz, Rosenmund, Jahn: "Reinvestigation of the role of snapin in neurotransmitter release." dans: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26251-6, (2004) (PubMed).

Détails sur SNAPIN

Antigène: SNAPIN (SNAP-Associated Protein (SNAPIN))

Autre désignation: Snapin (SNAPIN Produits)

Synonymes: anticorps SNAPAP, anticorps si:dkey-222b8.2, anticorps SNAPIN, anticorps BLOC1S7, anticorps BLOS7, anticorps 25kDa, anticorps AA407989, anticorps AV026596, anticorps Bloc1s7, anticorps Snap25bp, anticorps Snapap, anticorps SNAP associated protein, anticorps SNAP-associated protein L homeolog, anticorps SNAP-associated protein, anticorps SNAPIN, anticorps snapin.L, anticorps snapin, anticorps Snapin

Sujet: Synonyms: Snapap

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis