CCR4 anticorps
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- Antigène Voir toutes CCR4 Anticorps
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CCR4 est non-conjugé
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Application
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Specificité
- Anti-human CCR4
- Purification
- Protein G
- Immunogène
- immunisation with human CCR4 peptide
- Clone
- KH-4F5
- Isotype
- IgG2a
- Top Product
- Discover our top product CCR4 Anticorps primaire
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- Indications d'application
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Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Commentaires
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Synonyms: CC chemokine receptor 4
- Restrictions
- For Research Use only
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- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.2
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C
- Stockage commentaire
- short term: 2 °C - 8 °C, long term: -20 °C
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- Antigène
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- Autre désignation
- CCR4 (CCR4 Produits)
- Synonymes
- anticorps CC-CKR-4, anticorps CD194, anticorps CKR4, anticorps CMKBR4, anticorps ChemR13, anticorps HGCN:14099, anticorps K5-5, anticorps Ccr4, anticorps C-C CKR-4, anticorps CHEMR1, anticorps Cmkbr4, anticorps LESTR, anticorps Sdf1r, anticorps C-C motif chemokine receptor 4, anticorps chemokine (C-C motif) receptor 4, anticorps CCR4, anticorps Ccr4
- Sujet
- CCR4 (CC chemokine receptor 4) molecule belongs to the rhodopsin family of G-protein-coupled receptors. Chemokine receptors are membrane bound molecules composed of 7-transmembrane domains and coupled to G-proteins. CCR4 binds the chemokines CCL17 (TARC) and CCL22 (MDC) and is highly expressed in most single-positive CD4(+) thymocytes especially in TH2- and regulatory T-cells. It plays a central role in T cell migration to the thymus, T cell maturation and education. CCR4 is often up-regulated in inflammation and cause conformational changes that trigger intracellular signaling pathways.
- UniProt
- P51679
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