Cet anticorp Integrin beta 2 est conjugé à/à la PE
Application
Flow Cytometry (FACS)
Specificité
This antibody recognises the Porcine homologue of Human CD18. Clone PNK-I immunoprecipitates molecules of 166, 155 and 95 kDa under reducing and non-reducing conditions. Clone PNK-I has been reported to inhibit Porcine NK activity without affecting antibody-dependent cellular cytoxicity.
Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells in 10 l. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Reconstitution
Restore with 1.0 mL distilled water.
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % BSA and 5 % Sucrose
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store at +4 °C. This product should be stored undiluted. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf life: one year from despatch.
CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7