SIRPA anticorps

N° du produit ABIN1819095

Détail du produit anti-SIRPA anticorps

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reactivité: Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRPA est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: Porcine CD172a, a member of the signal regulatory protein (SIRP) family. Clone BL1H7 was originally clustered as SWC3 at the Third International Swine Cluster of Differentiation Workshop (,). CD172a is expressed on monocyte derived dendritic cells (MoDCs) also conventional (cDCs), plasmacytoid (pDCs) DCs and blood DCs.(, ). Clone BL1H7 immunoprecipitated a single band of ~90-110kD from preparations of biotinylated alveolar macrophages, a result confirmed by Western blotting analysis of alveolar macrophage lysates under non reducing conditions. Has proved a useful and reliable tool for immunohistochemical analysis of routinely processed, formalin fixed, paraffin embedded porcine tissues. Aberrant expression of CD172a has been noted on porcine leukemias with blast cells co-expressing lymphocytic markers CD5 and CD25 whilst expressing the Myeloid marker CD172a in a as opposed to the more characteristic of CD172+ cells seen in normal blood PBMC.

Purification: Protein G purified

Immunogène: Porcine alveolar macrophages.

Type of Immunogen: Cells

Clone: BL1H7

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Pig

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Store undiluted.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: CD172A / SIRPA (SIRPA Produits)

Synonymes: anticorps BIT, anticorps CD172A, anticorps MFR, anticorps MYD-1, anticorps P84, anticorps PTPNS1, anticorps SHPS1, anticorps SIRP, anticorps SIRPA, anticorps SIRP-A1, anticorps SIRP-B1, anticorps AI835480, anticorps Bit, anticorps CD172a, anticorps Ptpns1, anticorps SHP-1, anticorps SHPS-1, anticorps swc3, anticorps signal regulatory protein alpha, anticorps myeloperoxidase, anticorps signal-regulatory protein alpha, anticorps tyrosine-protein phosphatase non-receptor type substrate 1, anticorps SIRPA, anticorps MPO, anticorps LOC458039, anticorps LOC100400378, anticorps LOC100590224, anticorps Sirpa

Sujet: Name/Gene ID: SIRPA

Synonyms: SIRPA, CD172A, CD172a antigen, Inhibitory receptors shps-1, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, p84, SHPS-1, SHPS1, SIRP, Sirp-alpha-1, Sirp-alpha-3, Sirp-alpha1, MYD1, SIRPalpha, SIRPalpha2, BIT, MFR, MYD-1, PTPNS1, SHP substrate 1, Sirp-alpha-2

ID gène: 140885

UniProt: P78324