CD300a anticorps (FITC)

N° du produit ABIN1819154

Détail du produit anti-CD300a anticorps (FITC)

Antigène: CD300a (CD300A)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD300a est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: Recognizes human CD300a, otherwise known as IRp60 (inhibitory receptor protein 60), a 60kD transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells. Studies have shown that the cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro.

Purification: Protein G purified

Immunogène: Polyclonal population of NK cells.

Type of Immunogen: Cells

Clone: P192

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 1 % BSA, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur CD300a

Antigène: CD300a (CD300A)

Autre désignation: CD300A (CD300A Produits)

Synonymes: anticorps CD300L-B1, anticorps CD300A, anticorps clm8, anticorps B230315M08Rik, anticorps Clm8, anticorps LMIR1, anticorps MAIR-I, anticorps MAIR-Ia, anticorps MMAC8, anticorps Pigr4, anticorps mcpir1, anticorps CLM-8, anticorps CMRF-35-H9, anticorps CMRF-35H, anticorps CMRF35-H, anticorps CMRF35-H9, anticorps CMRF35H, anticorps CMRF35H9, anticorps IGSF12, anticorps IRC1, anticorps IRC1/IRC2, anticorps IRC2, anticorps IRp60, anticorps CD300 molecule like family member g, anticorps CD300a molecule, anticorps CMRF35-like molecule 8, anticorps CD300A molecule, anticorps Cd300a molecule, anticorps CD300LG, anticorps CD300A, anticorps LOC483289, anticorps clm8, anticorps Cd300a

Sujet: Name/Gene ID: CD300A

Synonyms: CD300A, CD300a antigen, CD300a molecule, CMRF35-like molecule 8, CMRF35-H, CMRF35-H9, CLM-8, CMRF35H9, IGSF12, Inhibitory receptor protein 60, IRC2, IRC1, NK inhibitory receptor, CMRF-35-H9, CMRF-35H, CMRF35H, IRC1a, IRp60, Leukocyte membrane antigen

ID gène: 11314

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process