SOS1 anticorps
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- Antigène Voir toutes SOS1 Anticorps
- SOS1 (Son of Sevenless Homolog 1 (SOS1))
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Reactivité
- Humain, Souris, Rat, Lapin, Cheval, Boeuf (Vache), Singe, Cobaye, Porc
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SOS1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Specificité
- Recognizes SOS1 (son of sevenless homolog 1), a ubiquitously expressed 150kD intracellular protein and bifunctional guanine nucleotide exchange factor (GEF), which plays a role in growth and differentiation signalling pathways and in actin reorganization, by acting as a regulator of Ras and Rac/Rho GTPases. Mutations in the SOS1 gene are responsible for the rare oral overgrowth condition known as gingival fibromatosis 1 (GINGF1), and also the cause of the relatively common autosomal dominant disorder Noonan syndrome type 4 (NS4), characterized by short stature, congenital heart malformation, bleeding diathesis and distinctive facial features.
- Purification
- Protein A purified
- Immunogène
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Synthetic peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human SOS1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Elephant, Panda, Bovine, Cat, Horse, Rabbit, Opossum, Guinea pig (100%), Dog, Turkey, Zebra finch (95%), Lizard (89%).
Type of Immunogen: Synthetic peptide - Clone
- SOS-1
- Isotype
- IgG1
- Top Product
- Discover our top product SOS1 Anticorps primaire
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- Indications d'application
- Approved: ELISA, IF, WB (1 μg/mL)
- Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Antigène
- SOS1 (Son of Sevenless Homolog 1 (SOS1))
- Autre désignation
- SOS1 / HGF (SOS1 Produits)
- Synonymes
- anticorps GF1, anticorps GGF1, anticorps GINGF, anticorps HGF, anticorps NS4, anticorps 4430401P03Rik, anticorps 9630010N06, anticorps AI449023, anticorps SOS Ras/Rac guanine nucleotide exchange factor 1, anticorps son of sevenless homolog 1 (Drosophila), anticorps SOS1, anticorps Sos1
- Classe de substances
- Viral Protein
- Sujet
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Name/Gene ID: SOS1
Synonyms: SOS1, GINGF, NS4, SOS-1, Son of sevenless homolog 1, GF1, GGF1 - ID gène
- 6654
- Pathways
- Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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