Prosaposin anticorps (AA 325-524)

N° du produit ABIN1845961

Détail du produit anti-Prosaposin anticorps

Antigène: Prosaposin (PSAP)

Épitope: AA 325-524

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Prosaposin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PSAP (AA: 325-524) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Détails sur Prosaposin

Antigène: Prosaposin (PSAP)

Autre désignation: PSAP (PSAP Produits)

Synonymes: anticorps GLBA, anticorps SAP1, anticorps AI037048, anticorps SGP-1, anticorps SGP1A, anticorps cb759, anticorps wu:fa14a06, anticorps wu:fb36e02, anticorps wu:fb58g07, anticorps PSAP, anticorps PSP-A, anticorps SFTPA1B, anticorps SP-A, anticorps prosaposin, anticorps surfactant protein A1, anticorps PSAP, anticorps Psap, anticorps psap, anticorps LOC100011417, anticorps LOC100304726, anticorps LOC100526719, anticorps SFTPA1

Sujet: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 58.1 kDa

ID gène: 5660

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity