NLRP3 anticorps (Internal Region)
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- Antigène Voir toutes NLRP3 Anticorps
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
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Épitope
- Internal Region
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NLRP3 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Fonction
- CIAS1 / Cryopyrin (Internal)
- Séquence
- DLYEKAKRDE PK
- Specificité
- This antibody is expected to recognise all five reported isoforms (NP_004886.3, NP_899632.1, NP_001230062.1, NP_001120933.1, NP_001120934.1). Reported variants represent identical protein (NP_004886.3 and NP_001073289.1).
- Réactivité croisée
- Boeuf (Vache), Chien, Humain, Souris, Porc, Rat
- Purification
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Classe de qualité
- Verified
- Immunogène
- Peptide with sequence C-DLYEKAKRDEPK, from the internal region of the protein sequence according to NP_004886.3, NP_899632.1, NP_001230062.1, NP_001120933.1, NP_001120934.1.
- Isotype
- IgG
- Top Product
- Discover our top product NLRP3 Anticorps primaire
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- Indications d'application
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Immunohistochemistry: In paraffin embedded Human Tonsil shows focal and interstitial staining of the inflammatory elements close to the epithelia of the tonsil crypts. Recommended concentration: 2-4 μg/mL.
Western Blot: Preliminary experiments gave an approx 70 kDa band in human lymph node and tonsil lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculat
Peptide ELISA: antibody detection limit dilution 1:64000.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Minimize freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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- Antigène
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
- Autre désignation
- NLRP3 (NLRP3 Produits)
- Synonymes
- anticorps CIAS1, anticorps Nalp3, anticorps avp, anticorps cias1, anticorps nalp3, anticorps pypaf1, anticorps agtavprl, anticorps AGTAVPRL, anticorps AII, anticorps AVP, anticorps C1orf7, anticorps CLR1.1, anticorps FCAS, anticorps FCU, anticorps MWS, anticorps NALP3, anticorps PYPAF1, anticorps AII/AVP, anticorps Cias1, anticorps Mmig1, anticorps Pypaf1, anticorps NLR family pyrin domain containing-like, anticorps NLR family pyrin domain containing 3, anticorps NLR family, pyrin domain containing 3 L homeolog, anticorps NLR family, pyrin domain containing 3, anticorps NLRPL, anticorps NLRP3, anticorps nlrp3.L, anticorps Nlrp3
- Sujet
- CIAS1, cold autoinflammatory syndrome 1, AGTAVPRL, AII/AVP, C1orf7, FCAS, FCU, MWS, NALP3, PYPAF1 , AII/AVP receptor-like, Muckle-Wells syndrome, NACHT, LRR and PYD containing protein 3, PYRIN-containing APAF1-like protein 1, angiotensin/vasopressin recep
- ID gène
- 114548
- NCBI Accession
- NP_004886, NP_899632, NP_001230062, NP_001120933, NP_001120934
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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