ACSL1 anticorps (C-Term)

N° du produit ABIN1881044

Détail du produit anti-ACSL1 anticorps

Antigène: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Épitope: AA 505-533, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACSL1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ACSL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-533 amino acids from the C-terminal region of human ACSL1.

Clone: RB42775

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ACSL1 (ABIN1881044)

Phillips, Goumidi, Bertrais, Field, Cupples, Ordovas, Defoort, Lovegrove, Drevon, Gibney, Blaak, Kiec-Wilk, Karlstrom, Lopez-Miranda, McManus, Hercberg, Lairon, Planells, Roche: "Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome." dans: Journal of lipid research, Vol. 51, Issue 7, pp. 1793-800, (2010) (PubMed).

Lu, Dollé, Imholz, van t Slot, Verschuren, Wijmenga, Feskens, Boer: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." dans: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).

Mashek, Bornfeldt, Coleman, Berger, Bernlohr, Black, DiRusso, Farber, Guo, Hashimoto, Khodiyar, Kuypers, Maltais, Nebert, Renieri, Schaffer, Stahl, Watkins, Vasiliou, Yamamoto: "Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family." dans: Journal of lipid research, Vol. 45, Issue 10, pp. 1958-61, (2004) (PubMed).

Détails sur ACSL1

Antigène: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Autre désignation: ACSL1 (Acsl1 Produits)

Synonymes: anticorps ACS1, anticorps FACL1, anticorps FACL2, anticorps LACS, anticorps LACS1, anticorps LACS2, anticorps Acas, anticorps Acas1, anticorps Acs, anticorps FACS, anticorps Facl2, anticorps ACS, anticorps COAA, anticorps zgc:110081, anticorps CER8, anticorps ECERIFERUM 8, anticorps LONG-CHAIN ACYL-COA SYNTHASE 1, anticorps T8I13.8, anticorps F13F21.14, anticorps F13F21_14, anticorps LATERAL ROOT DEVELOPMENT 2, anticorps LRD2, anticorps long-chain acyl-CoA synthetase 2, anticorps acyl-CoA synthetase long chain family member 1, anticorps acyl-CoA synthetase long-chain family member 1, anticorps acyl-CoA synthetase long chain family member 1a, anticorps AMP-dependent synthetase and ligase family protein, anticorps long-chain acyl-CoA synthetase 2, anticorps ACSL1, anticorps Acsl1, anticorps acsl1a, anticorps LACS1, anticorps LACS2

Sujet: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. [provided by RefSeq].

Poids moléculaire: 77943

NCBI Accession: NP_001986

UniProt: P33121

Pathways: Regulation of Lipid Metabolism by PPARalpha