This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This ADRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-397 amino acids from the C-terminal region of human ADRM1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Mazumdar, Gorgun, Sha, Tyryshkin, Zeng, Hartmann-Petersen, Jørgensen, Hendil, Eissa: "Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13)." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 31, pp. 13854-9, (2010) (PubMed).
Elangovan, Oh, Sukumaran, Wójcik, Yoo: "Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13." dans: Biochemical and biophysical research communications, Vol. 396, Issue 2, pp. 425-8, (2010) (PubMed).
Chen, Lee, Finley, Walters: "Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2." dans: Molecular cell, Vol. 38, Issue 3, pp. 404-15, (2010) (PubMed).
Chen, Hu, Shi, Zhang, He: "[Silencing of Adrm1 by RNA interference suppresses proliferation of colorectal cancer cells]." dans: Zhonghua zhong liu za zhi [Chinese journal of oncology], Vol. 31, Issue 11, pp. 815-9, (2010) (PubMed).
Kim, Ha, Kim, Yi, Lee, Choi: "Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation." dans: Biochemical and biophysical research communications, Vol. 390, Issue 3, pp. 585-90, (2009) (PubMed).
The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.