AKTIP anticorps (C-Term)

N° du produit ABIN1881052

Détail du produit anti-AKTIP anticorps

Antigène: AKTIP (AKT Interacting Protein (AKTIP))

Épitope: AA 262-288, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKTIP est non-conjugé

Application: Western Blotting (WB)

Homologie: C, Pr, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP.

Clone: RB38675

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-AKTIP (ABIN1881052)

Quaye, Dafou, Ramus, Song, Gentry-Maharaj, Maharaj, Notaridou, Hogdall, Kjaer, Christensen, Hogdall, Easton, Jacobs, Menon, Pharoah, Gayther: "Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival." dans: Human molecular genetics, Vol. 18, Issue 10, pp. 1869-78, (2009) (PubMed).

Xu, Sowa, Chen, Li, Gygi, Harper: "An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex." dans: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5059-71, (2008) (PubMed).

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." dans: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

Détails sur AKTIP

Antigène: AKTIP (AKT Interacting Protein (AKTIP))

Autre désignation: AKTIP (AKTIP Produits)

Synonymes: anticorps FT1, anticorps FTS, anticorps cb798, anticorps fts, anticorps zgc:77699, anticorps fts-A, anticorps aktip, anticorps fts-B, anticorps MGC133931, anticorps AL023020, anticorps Fif, anticorps Ft, anticorps Ft1, anticorps Fts, anticorps AKT interacting protein, anticorps akt interacting protein, anticorps AKT interacting protein L homeolog, anticorps AKT interacting protein S homeolog, anticorps thymoma viral proto-oncogene 1 interacting protein, anticorps AKTIP, anticorps aktip, anticorps aktip.L, anticorps aktip.S, anticorps Aktip

Sujet: The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.

Poids moléculaire: 33128

NCBI Accession: NP_001012398, NP_071921

UniProt: Q9H8T0