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Angiomotin anticorps (pTyr599)

AMOT Reactivité: Humain DB Hôte: Lapin Polyclonal RB41443 unconjugated
N° du produit ABIN1881054
  • Antigène Voir toutes Angiomotin (AMOT) Anticorps
    Angiomotin (AMOT)
    Épitope
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr599
    Reactivité
    • 59
    • 14
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 49
    • 10
    Lapin
    Clonalité
    • 53
    • 6
    Polyclonal
    Conjugué
    • 32
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Angiomotin est non-conjugé
    Application
    • 39
    • 33
    • 13
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Dot Blot (DB)
    Homologie
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This AMOT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y599 of human AMOT.
    Clone
    RB41443
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AMOT Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Heller, Adu-Gyamfi, Smith-Kinnaman, Babbey, Vora, Xue, Bittman, Stahelin, Wells: "Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain." dans: The Journal of biological chemistry, Vol. 285, Issue 16, pp. 12308-20, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Gagné, Moreau, Plourde, Lapointe, Lord, Gagnon, Fernandes: "Human angiomotin-like 1 associates with an angiomotin protein complex through its coiled-coil domain and induces the remodeling of the actin cytoskeleton." dans: Cell motility and the cytoskeleton, Vol. 66, Issue 9, pp. 754-68, (2009) (PubMed).

    Zheng, Vertuani, Nyström, Audebert, Meijer, Tegnebratt, Borg, Uhlén, Majumdar, Holmgren: "Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis." dans: Circulation research, Vol. 105, Issue 3, pp. 260-70, (2009) (PubMed).

    Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

  • Antigène
    Angiomotin (AMOT)
    Autre désignation
    AMOT (AMOT Produits)
    Synonymes
    anticorps C81439, anticorps CAG-2, anticorps D0Kist1, anticorps E230009N18Rik, anticorps Sii6, anticorps mKIAA1071, anticorps RGD1564027, anticorps si:dkey-13f9.6, anticorps wu:fj21a07, anticorps angiomotin, anticorps microRNA 4329, anticorps AMOT, anticorps Amot, anticorps MIR4329, anticorps amot
    Sujet
    This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Poids moléculaire
    118085
    NCBI Accession
    NP_001106962, NP_573572
    UniProt
    Q4VCS5
    Pathways
    Cell-Cell Junction Organization, Regulation of Cell Size
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