This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This mouse BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S96 of mouse BAD.
BAD
Reactivité: Humain, Souris
WB, IHC (p), FACS
Hôte: Lapin
Polyclonal
RB4617
unconjugated
Indications d'application
DB: 1:500
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Kim, Xin, Moioli, Chung, Lee, Chen, Fu, Koch, Mao: "Regeneration of dental-pulp-like tissue by chemotaxis-induced cell homing." dans: Tissue engineering. Part A, Vol. 16, Issue 10, pp. 3023-31, (2010) (PubMed).
Frenzel, Labi, Chmelewskij, Ploner, Geley, Fiegl, Tzankov, Villunger: "Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad." dans: Blood, Vol. 115, Issue 5, pp. 995-1005, (2010) (PubMed).
Quoyer, Longuet, Broca, Linck, Costes, Varin, Bockaert, Bertrand, Dalle: "GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells." dans: The Journal of biological chemistry, Vol. 285, Issue 3, pp. 1989-2002, (2010) (PubMed).
Wu, Wang, Schroer, Choi, Chen, Okada, Woo: "Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice." dans: Diabetologia, Vol. 52, Issue 10, pp. 2130-41, (2009) (PubMed).
Polzien, Baljuls, Rennefahrt, Fischer, Schmitz, Zahedi, Sickmann, Metz, Albert, Benz, Hekman, Rapp: "Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation." dans: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28004-20, (2009) (PubMed).
anticorps bad, anticorps fa01b12, anticorps wu:fa01b12, anticorps wu:fa96d04, anticorps BAD, anticorps BBC2, anticorps BCL2L8, anticorps AI325008, anticorps Bbc2, anticorps BCL2-associated agonist of cell death b, anticorps BCL2 associated agonist of cell death, anticorps BCL2-associated agonist of cell death, anticorps badb, anticorps BAD, anticorps Bad
Sujet
BAD promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.