BLMH anticorps (AA 212-242)
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- Antigène Voir toutes BLMH Anticorps
- BLMH (Bleomycin Hydrolase (BLMH))
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Épitope
- AA 212-242
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BLMH est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Rb
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This BLMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BLMH.
- Isotype
- Ig Fraction
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- Indications d'application
- WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." dans: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).
: "Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization." dans: Biochemistry, Vol. 35, Issue 21, pp. 6706-14, (1996) (PubMed).
: "
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Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." dans: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).
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- Antigène
- BLMH (Bleomycin Hydrolase (BLMH))
- Autre désignation
- BLMH (BLMH Produits)
- Sujet
- The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).
- Poids moléculaire
- 52562
- NCBI Accession
- NP_000377
- UniProt
- Q13867
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