This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This C8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-422 amino acids from the C-terminal region of human C8B.
C8B
Reactivité: Humain, Rat
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Han, Lan, Park, Lee, Park, Ahn, Shin, Kang, Koo, Seo, Choi, Ahn, Chanock, Kim, Rothman, Kang: "Polymorphisms in innate immunity genes and risk of childhood leukemia." dans: Human immunology, Vol. 71, Issue 7, pp. 727-30, (2010) (PubMed).
Rajaraman, Brenner, Neta, Pfeiffer, Wang, Yeager, Thomas, Fine, Linet, Rothman, Chanock, Inskip: "Risk of meningioma and common variation in genes related to innate immunity." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, (2010) (PubMed).
Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." dans: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.