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CASQ2 anticorps (AA 79-107)

CASQ2 Reactivité: Humain WB Hôte: Lapin Polyclonal RB41817 unconjugated
N° du produit ABIN1881138
  • Antigène Voir toutes CASQ2 Anticorps
    CASQ2 (Calsequestrin 2 (CASQ2))
    Épitope
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 79-107
    Reactivité
    • 31
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 27
    • 5
    Lapin
    Clonalité
    • 28
    • 4
    Polyclonal
    Conjugué
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CASQ2 est non-conjugé
    Application
    • 21
    • 16
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    Rb
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This CASQ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.
    Clone
    RB41817
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CASQ2 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Kirchhefer, Wehrmeister, Postma, Pohlentz, Mormann, Kucerova, Müller, Schmitz, Schulze-Bahr, Wilde, Neumann: "The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling." dans: Journal of molecular and cellular cardiology, Vol. 49, Issue 1, pp. 95-105, (2010) (PubMed).

    Wei, Hanna, Beard, Dulhunty: "Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle." dans: Cell calcium, Vol. 45, Issue 5, pp. 474-84, (2009) (PubMed).

  • Antigène
    CASQ2 (Calsequestrin 2 (CASQ2))
    Autre désignation
    CASQ2 (CASQ2 Produits)
    Synonymes
    anticorps CASQ2, anticorps DKFZp468D075, anticorps AA033488, anticorps AW146219, anticorps ESTM52, anticorps cCSQ, anticorps PDIB2, anticorps cardCSQ, anticorps CASQ1, anticorps CAL, anticorps calsequestrin 2, anticorps CASQ2, anticorps Casq2
    Sujet
    The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq].
    Poids moléculaire
    46436
    NCBI Accession
    NP_001223
    UniProt
    O14958
    Pathways
    Negative Regulation of Transporter Activity
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