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Cyclin B2 anticorps (pSer10)

CCNB2 Reactivité: Humain DB Hôte: Lapin Polyclonal RB42143 unconjugated
N° du produit ABIN1881156
  • Antigène Voir toutes Cyclin B2 (CCNB2) Anticorps
    Cyclin B2 (CCNB2)
    Épitope
    • 15
    • 14
    • 14
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer10
    Reactivité
    • 90
    • 30
    • 14
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 98
    • 6
    • 3
    Lapin
    Clonalité
    • 93
    • 14
    Polyclonal
    Conjugué
    • 41
    • 10
    • 10
    • 9
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cyclin B2 est non-conjugé
    Application
    • 56
    • 49
    • 39
    • 14
    • 13
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Dot Blot (DB)
    Homologie
    Pr
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This CCNB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human CCNB2.
    Clone
    RB42143
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CCNB2 Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Haraguchi, Ishikawa, Yamaguchi, Fujisawa: "Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia." dans: Fertility and sterility, Vol. 91, Issue 4 Suppl, pp. 1424-6, (2009) (PubMed).

    De Martino, Visone, Wierinckx, Palmieri, Ferraro, Cappabianca, Chiappetta, Forzati, Lombardi, Colao, Trouillas, Fedele, Fusco: "HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas." dans: Cancer research, Vol. 69, Issue 5, pp. 1844-50, (2009) (PubMed).

    Cunningham, Vierkant, Sellers, Phelan, Rider, Liebow, Schildkraut, Berchuck, Couch, Wang, Fridley, Gentry-Maharaj, Menon, Hogdall, Kjaer, Whittemore, DiCioccio, Song, Gayther, Ramus, Pharaoh, Goode: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." dans: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).

    Bellanger, de Gramont, Sobczak-Thépot: "Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2." dans: Oncogene, Vol. 26, Issue 51, pp. 7175-84, (2007) (PubMed).

    Stav, Bar, Sandbank: "Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma." dans: The International journal of biological markers, Vol. 22, Issue 2, pp. 108-13, (2007) (PubMed).

  • Antigène
    Cyclin B2 (CCNB2)
    Autre désignation
    CCNB2 (CCNB2 Produits)
    Synonymes
    anticorps HsT17299, anticorps CycB2, anticorps sb:cb303, anticorps cycB2, anticorps LOC100136691, anticorps C-B2, anticorps cyclinb2, anticorps hst17299, anticorps LOC100282653, anticorps cyclin B2, anticorps cyclin B2 S homeolog, anticorps CCNB2, anticorps Ccnb2, anticorps ccnb2, anticorps LOC100136691, anticorps LOC100282653, anticorps ccnb2.S
    Sujet
    Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
    Poids moléculaire
    45282
    NCBI Accession
    NP_004692
    UniProt
    O95067
    Pathways
    Cycle Cellulaire, M Phase
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