CDCA7L anticorps (C-Term)

N° du produit ABIN1881189

Détail du produit anti-CDCA7L anticorps

Antigène: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Épitope: AA 290-317, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDCA7L est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CDCA7L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CDCA7L.

Clone: RB43388

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CDCA7L (ABIN1881189)

Huang, Ho, Ponzielli, Barsyte-Lovejoy, Bouffet, Picard, Hawkins, Penn: "Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells." dans: Cancer research, Vol. 65, Issue 13, pp. 5607-19, (2005) (PubMed).

Chen, Ou, Chen, Choi, Shih: "R1, a novel repressor of the human monoamine oxidase A." dans: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 11552-9, (2005) (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." dans: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

Détails sur CDCA7L

Antigène: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Autre désignation: CDCA7L (CDCA7L Produits)

Synonymes: anticorps ram2, anticorps MGC154777, anticorps BC006933, anticorps JPO2, anticorps R1, anticorps RAM2, anticorps RAPGEF5, anticorps cell division cycle associated 7 like, anticorps cell division cycle associated 7 like L homeolog, anticorps cell division cycle-associated 7-like protein, anticorps CDCA7L, anticorps cdca7l.L, anticorps LOC100454683, anticorps Cdca7l

Sujet: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways, May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

UniProt: B3KTR5