CHN1 anticorps (N-Term)

N° du produit ABIN1881198

Détail du produit anti-CHN1 anticorps

Antigène: CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHN1 est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CHN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHN1.

Clone: RB42774

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CHN1 (ABIN1881198)

Volk, Fricke, Strobl, Kolling, Kubisch, Neugebauer: "Analysis of the CHN1 gene in patients with various types of congenital ocular motility disorders." dans: Graefe's archive for clinical and experimental ophthalmology, Vol. 248, Issue 9, pp. 1351-7, (2010) (PubMed).

Murillo-Correa, Kon-Jara, Engle, Zenteno: "Clinical features associated with an I126M alpha2-chimaerin mutation in a family with autosomal-dominant Duane retraction syndrome." dans: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus, Vol. 13, Issue 3, pp. 245-8, (2009) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." dans: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Détails sur CHN1

Antigène: CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))

Autre désignation: CHN1 (ARHGAP2 Produits)

Synonymes: anticorps ARHGAP2, anticorps CHN, anticorps DURS2, anticorps NC, anticorps RHOGAP2, anticorps 0610007I19Rik, anticorps 0710001E19Rik, anticorps 1700112L09Rik, anticorps 2900046J01Rik, anticorps AI413815, anticorps chimaerin, anticorps wu:fr89a09, anticorps zgc:56160, anticorps zgc:92906, anticorps N-chimaerin, anticorps chimerin 1, anticorps chimerin 1 L homeolog, anticorps CHN1, anticorps Chn1, anticorps chn1.L, anticorps chn1

Sujet: This gene encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane's retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 53172

NCBI Accession: NP_001020372, NP_001193531, NP_001813

UniProt: P15882