This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This DIRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human DIRC2.
DIRC2
Reactivité: Humain, Rat
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 647
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Bodmer, Eleveld, Kater-Baats, Janssen, Janssen, Weterman, Schoenmakers, Nickerson, Linehan, Zbar, van Kessel: "Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21)." dans: Human molecular genetics, Vol. 11, Issue 6, pp. 641-9, (2002) (PubMed).
Bodmer, Janssen, Jonkers, van den Berg, Dijkhuizen, Debiec-Rychter, Schoenmakers, van Kessel: "Molecular cytogenetic analysis of clustered sporadic and familial renal cell carcinoma-associated 3q13 approximately q22 breakpoints." dans: Cancer genetics and cytogenetics, Vol. 136, Issue 2, pp. 95-100, (2002) (PubMed).
anticorps MGC80843, anticorps zgc:92095, anticorps rcc4, anticorps MGC69320, anticorps RCC4, anticorps disrupted in renal carcinoma 2, anticorps disrupted in renal carcinoma 2 L homeolog, anticorps disrupted in renal carcinoma 2 (human), anticorps DIRC2, anticorps dirc2.L, anticorps dirc2, anticorps Dirc2
Sujet
This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.