DPEP1 anticorps (N-Term)

N° du produit ABIN1881269

Détail du produit anti-DPEP1 anticorps

Antigène: DPEP1 (Dipeptidase 1 (Renal) (DPEP1))

Épitope: AA 1-30, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPEP1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1.

Clone: RB41566

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur DPEP1

Antigène: DPEP1 (Dipeptidase 1 (Renal) (DPEP1))

Autre désignation: DPEP1 (DPEP1 Produits)

Synonymes: anticorps AI327012, anticorps MBD, anticorps MBD1, anticorps MDP, anticorps RDP, anticorps dipeptidase 1 (renal), anticorps dipeptidase 1, anticorps DPEP1, anticorps Dpep1

Sujet: DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982 [PubMed 6122685]). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984 [PubMed 6334084]). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990 [PubMed 2303490]).

Poids moléculaire: 45674

NCBI Accession: NP_001121613, NP_004404

UniProt: P16444

Pathways: Inositol Metabolic Process