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ENPP1 anticorps (N-Term)

ENPP1 Reactivité: Humain WB Hôte: Lapin Polyclonal RB41733 unconjugated
N° du produit ABIN1881296
  • Antigène Voir toutes ENPP1 Anticorps
    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
    Épitope
    • 15
    • 14
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 6-34, N-Term
    Reactivité
    • 42
    • 37
    • 11
    • 7
    • 4
    Humain
    Hôte
    • 74
    • 5
    • 2
    • 2
    Lapin
    Clonalité
    • 78
    • 5
    Polyclonal
    Conjugué
    • 22
    • 13
    • 12
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ENPP1 est non-conjugé
    Application
    • 66
    • 35
    • 14
    • 14
    • 11
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ENPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human ENPP1.
    Clone
    RB41733
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ENPP1 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Ermakov, Rosenbaum, Malkin, Livshits: "Family-based study of association between ENPP1 genetic variants and craniofacial morphology." dans: Annals of human biology, Vol. 37, Issue 6, pp. 754-66, (2010) (PubMed).

    Wang, Peng, Qu, Huang: "[Association and meta-analysis of ENPP1 K121Q with type 2 diabetes in Han Chinese.]." dans: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 32, Issue 8, pp. 808-16, (2010) (PubMed).

    Cruz, Valladares-Salgado, Garcia-Mena, Ross, Edwards, Angeles-Martinez, Ortega-Camarillo, de la Peña, Burguete-Garcia, Wacher-Rodarte, Ambriz, Rivera, Dartote, Peralta, Parra, Kumate: "Candidate gene association study conditioning on individual ancestry in patients with type 2 diabetes and metabolic syndrome from Mexico City." dans: Diabetes/metabolism research and reviews, Vol. 26, Issue 4, pp. 261-70, (2010) (PubMed).

    Moehlecke, Kramer, Leitão, Krahe, Balbosco, Azevedo, Gross, Canani: "[ENPP1 K121Q polymorphism and ischemic heart disease in diabetic patients]." dans: Arquivos brasileiros de cardiologia, Vol. 94, Issue 2, pp. 157-61, 168-73, 159-63, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

  • Antigène
    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
    Autre désignation
    ENPP1 (ENPP1 Produits)
    Synonymes
    anticorps ENPP1, anticorps si:ch211-142e24.2, anticorps zgc:136238, anticorps ARHR2, anticorps M6S1, anticorps NPP1, anticorps NPPS, anticorps PC-1, anticorps PCA1, anticorps PDNP1, anticorps 4833416E15Rik, anticorps AI428932, anticorps C76301, anticorps CD203c, anticorps E-NPP1, anticorps Ly-41, anticorps Npps, anticorps Pca, anticorps Pca-1, anticorps Pdnp1, anticorps ttw, anticorps twy, anticorps Pc1, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 1, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 1 L homeolog, anticorps ENPP1, anticorps enpp1, anticorps enpp1.L, anticorps Enpp1
    Sujet
    This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
    Poids moléculaire
    104924
    NCBI Accession
    NP_006199
    UniProt
    P22413
    Pathways
    Regulation of Carbohydrate Metabolic Process
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