FMO5 anticorps (C-Term)

N° du produit ABIN1881348

Détail du produit anti-FMO5 anticorps

Antigène: FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Épitope: AA 474-502, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FMO5 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FMO5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human FMO5.

Clone: RB42789

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-FMO5 (ABIN1881348)

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." dans: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Furnes, Feng, Sommer, Schlenk: "Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 31, Issue 2, pp. 187-93, (2003) (PubMed).

Détails sur FMO5

Antigène: FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Autre désignation: FMO5 (FMO5 Produits)

Synonymes: anticorps MGC68633, anticorps MGC108355, anticorps sb:cb1007, anticorps wu:fc05b01, anticorps wu:fk47g04, anticorps 5033418D19Rik, anticorps AI195026, anticorps flavin containing monooxygenase 5 S homeolog, anticorps flavin containing monooxygenase 5, anticorps fmo5.S, anticorps fmo5, anticorps MCYG_00559, anticorps FMO5, anticorps Fmo5

Sujet: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 60221

NCBI Accession: NP_001138301, NP_001138302, NP_001452

UniProt: P49326