GATM anticorps (C-Term)

N° du produit ABIN1881365

Détail du produit anti-GATM anticorps

Antigène: GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

Épitope: AA 350-378, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATM est non-conjugé

Application: Western Blotting (WB)

Homologie: B, Pr, M, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human GATM.

Clone: RB41023

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-GATM (ABIN1881365)

Köttgen, Glazer, Dehghan, Hwang, Katz, Li, Yang, Gudnason, Launer, Harris, Smith, Arking, Astor, Boerwinkle, Ehret, Ruczinski: "Multiple loci associated with indices of renal function and chronic kidney disease." dans: Nature genetics, Vol. 41, Issue 6, pp. 712-7, (2010) (PubMed).

Köttgen, Pattaro, Böger, Fuchsberger, Olden, Glazer, Parsa, Gao, Yang, Smith, OConnell, Li, Schmidt, Tanaka, Isaacs, Ketkar, Hwang, Johnson, Dehghan, Teumer, Paré, Atkinson, Zeller, Lohman et al.: "New loci associated with kidney function and chronic kidney disease...." dans: Nature genetics, Vol. 42, Issue 5, pp. 376-84, (2010) (PubMed).

Lion-François, Cheillan, Pitelet, Acquaviva-Bourdain, Bussy, Cotton, Guibaud, Gérard, Rivier, Vianey-Saban, Jakobs, Salomons, des Portes: "High frequency of creatine deficiency syndromes in patients with unexplained mental retardation." dans: Neurology, Vol. 67, Issue 9, pp. 1713-4, (2006) (PubMed).

Détails sur GATM

Antigène: GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

Autre désignation: GATM (GATM Produits)

Synonymes: anticorps AT, anticorps AGAT, anticorps CCDS3, anticorps 1810003P21Rik, anticorps AI314789, anticorps cb409, anticorps wu:fa08a06, anticorps zgc:65855, anticorps glycine amidinotransferase (L-arginine:glycine amidinotransferase) L homeolog, anticorps glycine amidinotransferase, anticorps glycine amidinotransferase (L-arginine:glycine amidinotransferase), anticorps gatm.L, anticorps GATM, anticorps Gatm, anticorps gatm

Sujet: This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

Poids moléculaire: 48455

NCBI Accession: NP_001473

UniProt: P50440