This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This GDI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the C-terminal region of human GDI1.
GDI1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:2000. WB: 1:1000-1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Massignan, Biasini, Lauranzano, Veglianese, Pignataro, Fioriti, Harris, Salmona, Chiesa, Bonetto: "Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway." dans: Molecular & cellular proteomics : MCP, Vol. 9, Issue 4, pp. 611-22, (2010) (PubMed).
Martins-de-Souza, Schmitt, Röder, Lebar, Schneider-Axmann, Falkai, Turck: "Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia." dans: Journal of psychiatric research, Vol. 44, Issue 14, pp. 989-91, (2010) (PubMed).
Chen, Deng, Zhang, Yang, Xie, Xu: "GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation." dans: The Biochemical journal, Vol. 422, Issue 2, pp. 229-35, (2009) (PubMed).
Zhang, DU, Zheng, Gao, Huang, Li, Chen, Zhang: "[Relationship between the polymorphisms of GDI1, children NSMR and their intelligence in Qinba region]." dans: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 30, Issue 5, pp. 590-4, (2008) (PubMed).
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.