This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This GNA11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GNA11.
GNA11
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Zhao, Zou, Li, Li, Wu, Li, Wang, Zheng: "Expression of G-protein subunit ?-14 is increased in human placentas from preeclamptic pregnancies." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 62, Issue 5, pp. 347-54, (2014) (PubMed).
Gavard, Gutkind: "Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q." dans: The Journal of biological chemistry, Vol. 283, Issue 44, pp. 29888-96, (2008) (PubMed).
Durchánková, Novotný, Svoboda: "The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis." dans: Physiological research / Academia Scientiarum Bohemoslovaca, Vol. 57, Issue 2, pp. 195-203, (2008) (PubMed).
Shankaranarayanan, Thal, Tesmer, Roman, Neubig, Kozasa, Tesmer: "Assembly of high order G alpha q-effector complexes with RGS proteins." dans: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34923-34, (2008) (PubMed).
Luttrell: "Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors." dans: Molecular biotechnology, Vol. 39, Issue 3, pp. 239-64, (2008) (PubMed).
Hildebrand, David, Hamid, Mulatz, Garcia, Zamponi, Snutch: "Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors." dans: The Journal of biological chemistry, Vol. 282, Issue 29, pp. 21043-55, (2007) (PubMed).
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.