This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This Mouse Gpi antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-558 amino acids from the C-terminal region of mouse Gpi.
GPI
Reactivité: Humain, Souris, Rat
IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
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Chandele, Joshi, Zhu, Paul, Leonard, Kaech: "Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 8, pp. 5309-19, (2008) (PubMed).
Cuda, Wan, Sobel, Croker, Morel: "Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 11, pp. 7439-47, (2007) (PubMed).
Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.