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GUCA1B anticorps (N-Term)

GUCA1B Reactivité: Humain WB Hôte: Lapin Polyclonal RB40485 unconjugated
N° du produit ABIN1881399
  • Antigène Voir toutes GUCA1B Anticorps
    GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))
    Épitope
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 29-57, N-Term
    Reactivité
    • 21
    • 11
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 21
    • 1
    Lapin
    Clonalité
    • 21
    • 1
    Polyclonal
    Conjugué
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GUCA1B est non-conjugé
    Application
    • 15
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This GUCA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human GUCA1B.
    Clone
    RB40485
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Sato, Nakazawa, Usui, Tanimoto, Abe, Ohguro: "Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies." dans: Graefe's archive for clinical and experimental ophthalmology, Vol. 243, Issue 3, pp. 235-42, (2005) (PubMed).

    Nishiguchi, Sokal, Yang, Roychowdhury, Palczewski, Berson, Dryja, Baehr: "A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration." dans: Investigative ophthalmology & visual science, Vol. 45, Issue 11, pp. 3863-70, (2004) (PubMed).

    Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." dans: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

  • Antigène
    GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))
    Autre désignation
    GUCA1B (GUCA1B Produits)
    Sujet
    The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq].
    Poids moléculaire
    23420
    NCBI Accession
    NP_002089
    UniProt
    Q9UMX6
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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