GUCA1C anticorps (C-Term)

N° du produit ABIN1881400

Détail du produit anti-GUCA1C anticorps

Antigène: GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))

Épitope: AA 171-199, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GUCA1C est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.

Clone: RB42656

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-GUCA1C (ABIN1881400)

Stephen, Palczewski, Sousa: "The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies." dans: Journal of molecular biology, Vol. 359, Issue 2, pp. 266-75, (2006) (PubMed).

Imanishi, Li, Sokal, Sowa, Lichtarge, Wensel, Saperstein, Baehr, Palczewski: "Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man." dans: The European journal of neuroscience, Vol. 15, Issue 1, pp. 63-78, (2002) (PubMed).

Haeseleer, Sokal, Li, Pettenati, Rao, Bronson, Wechter, Baehr, Palczewski: "Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily." dans: The Journal of biological chemistry, Vol. 274, Issue 10, pp. 6526-35, (1999) (PubMed).

Détails sur GUCA1C

Antigène: GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))

Autre désignation: GUCA1C (GUCA1C Produits)

Synonymes: anticorps gcap3, anticorps GCAP3, anticorps guanylate cyclase activator 1C, anticorps guca1c, anticorps GUCA1C

Sujet: GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.

Poids moléculaire: 23822

NCBI Accession: NP_005450

UniProt: O95843

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction