HIST2H2AC anticorps (AA 18-46)

N° du produit ABIN1881417

Détail du produit anti-HIST2H2AC anticorps

Antigène: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Épitope: AA 18-46

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIST2H2AC est non-conjugé

Application: Western Blotting (WB)

Homologie: Rat, B, X, M, C, Pr, Zf, D

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.

Clone: RB41799

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-HIST2H2AC (ABIN1881417)

Ishibashi, Dryhurst, Rose, Shabanowitz, Hunt, Ausió: "Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome." dans: Biochemistry, Vol. 48, Issue 22, pp. 5007-17, (2009) (PubMed).

Karaczyn, Cheng, Buzard, Hartley, Esposito, Kasprzak: "Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects." dans: Annals of clinical and laboratory science, Vol. 39, Issue 3, pp. 251-62, (2009) (PubMed).

Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." dans: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

Détails sur HIST2H2AC

Antigène: HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

Autre désignation: HIST2H2AC (HIST2H2AC Produits)

Synonymes: anticorps HIST2H2AC, anticorps H2A, anticorps H2A-GL101, anticorps H2A/q, anticorps H2AFQ, anticorps H2a-613b, anticorps RGD1560965, anticorps histone cluster 1, H2A, IV, anticorps histone cluster 2 H2A family member c, anticorps histone cluster 2, H2ac, anticorps HIST1H2A4, anticorps HIST2H2AC, anticorps Hist2h2ac

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.

Poids moléculaire: 13988

NCBI Accession: NP_003508

UniProt: Q16777