HPS5 anticorps (N-Term)

N° du produit ABIN1881436

Détail du produit anti-HPS5 anticorps

Antigène: HPS5 (Hermansky-Pudlak Syndrome 5 (HPS5))

Épitope: AA 88-116, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HPS5 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HPS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human HPS5.

Clone: RB42226

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-HPS5 (ABIN1881436)

Helip-Wooley, Westbroek, Dorward, Koshoffer, Huizing, Boissy, Gahl: "Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5." dans: The Journal of investigative dermatology, Vol. 127, Issue 6, pp. 1471-8, (2007) (PubMed).

Huizing, Parkes, Helip-Wooley, White, Gahl: "Platelet alpha granules in BLOC-2 and BLOC-3 subtypes of Hermansky-Pudlak syndrome." dans: Platelets, Vol. 18, Issue 2, pp. 150-7, (2007) (PubMed).

Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." dans: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).

Huizing, Hess, Dorward, Claassen, Helip-Wooley, Kleta, Kaiser-Kupfer, White, Gahl: "Cellular, molecular and clinical characterization of patients with Hermansky-Pudlak syndrome type 5." dans: Traffic (Copenhagen, Denmark), Vol. 5, Issue 9, pp. 711-22, (2004) (PubMed).

Di Pietro, Falcón-Pérez, DellAngelica: "Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6." dans: Traffic (Copenhagen, Denmark), Vol. 5, Issue 4, pp. 276-83, (2004) (PubMed).

Détails sur HPS5

Antigène: HPS5 (Hermansky-Pudlak Syndrome 5 (HPS5))

Autre désignation: HPS5 (HPS5 Produits)

Synonymes: anticorps AIBP63, anticorps Aa2-028, anticorps Ab1-018, anticorps zgc:162420, anticorps AI646796, anticorps AL022647, anticorps C85120, anticorps haze, anticorps hz, anticorps maroon, anticorps mr, anticorps ru-2, anticorps ru2, anticorps HPS5, biogenesis of lysosomal organelles complex 2 subunit 2, anticorps Hermansky-Pudlak syndrome 5, anticorps HPS5, anticorps Hps5, anticorps hps5

Sujet: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.

Poids moléculaire: 127449

NCBI Accession: NP_009147, NP_852608, NP_852609

UniProt: Q9UPZ3