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HPS5 anticorps (N-Term)

HPS5 Reactivité: Humain WB Hôte: Lapin Polyclonal RB42226 unconjugated
N° du produit ABIN1881436
  • Antigène Voir toutes HPS5 Anticorps
    HPS5 (Hermansky-Pudlak Syndrome 5 (HPS5))
    Épitope
    • 15
    • 13
    • 6
    AA 88-116, N-Term
    Reactivité
    • 16
    • 15
    • 1
    Humain
    Hôte
    • 30
    Lapin
    Clonalité
    • 30
    Polyclonal
    Conjugué
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HPS5 est non-conjugé
    Application
    • 30
    • 17
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This HPS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human HPS5.
    Clone
    RB42226
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Helip-Wooley, Westbroek, Dorward, Koshoffer, Huizing, Boissy, Gahl: "Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5." dans: The Journal of investigative dermatology, Vol. 127, Issue 6, pp. 1471-8, (2007) (PubMed).

    Huizing, Parkes, Helip-Wooley, White, Gahl: "Platelet alpha granules in BLOC-2 and BLOC-3 subtypes of Hermansky-Pudlak syndrome." dans: Platelets, Vol. 18, Issue 2, pp. 150-7, (2007) (PubMed).

    Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." dans: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).

    Huizing, Hess, Dorward, Claassen, Helip-Wooley, Kleta, Kaiser-Kupfer, White, Gahl: "Cellular, molecular and clinical characterization of patients with Hermansky-Pudlak syndrome type 5." dans: Traffic (Copenhagen, Denmark), Vol. 5, Issue 9, pp. 711-22, (2004) (PubMed).

    Di Pietro, Falcón-Pérez, DellAngelica: "Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6." dans: Traffic (Copenhagen, Denmark), Vol. 5, Issue 4, pp. 276-83, (2004) (PubMed).

  • Antigène
    HPS5 (Hermansky-Pudlak Syndrome 5 (HPS5))
    Autre désignation
    HPS5 (HPS5 Produits)
    Synonymes
    anticorps AIBP63, anticorps Aa2-028, anticorps Ab1-018, anticorps zgc:162420, anticorps AI646796, anticorps AL022647, anticorps C85120, anticorps haze, anticorps hz, anticorps maroon, anticorps mr, anticorps ru-2, anticorps ru2, anticorps HPS5, biogenesis of lysosomal organelles complex 2 subunit 2, anticorps Hermansky-Pudlak syndrome 5, anticorps HPS5, anticorps Hps5, anticorps hps5
    Sujet
    This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.
    Poids moléculaire
    127449
    NCBI Accession
    NP_009147, NP_852608, NP_852609
    UniProt
    Q9UPZ3
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