This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This HSPA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-571 amino acids from the C-terminal region of human HSPA6.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Leung, Hall, Rajendran, Spurr, Lim: "The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1." dans: Genomics, Vol. 12, Issue 1, pp. 74-9, (1992) (PubMed).
Antigène
HSPA6
(Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))
anticorps HSPA6, anticorps HSP70B', anticorps heat shock protein family A (Hsp70) member 6, anticorps HSPA6
Sujet
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.