ICT1 anticorps (C-Term)

N° du produit ABIN1881444

Détail du produit anti-ICT1 anticorps

Antigène: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Épitope: AA 153-179, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ICT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ICT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-179 amino acids from the C-terminal region of human ICT1.

Clone: RB42881

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ICT1 (ABIN1881444)

Wang, He, Zhang, Yang, Wang, Liu, Wu: "Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells." dans: Technology in cancer research & treatment, Vol. 16, Issue 5, pp. 559-569, (2018) (PubMed).

Tao, Song, Han, Wang, Zhao, Gu: "miR-205 regulation of ICT1 has an oncogenic potential via promoting the migration and invasion of gastric cancer cells." dans: Biomedicine & pharmacotherapy, Vol. 96, pp. 191-197, (2018) (PubMed).

Wang, Jin, Wu, Wang, Li: "Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells." dans: Acta biochimica et biophysica Sinica, Vol. 49, Issue 11, pp. 979-988, (2018) (PubMed).

Chang, Yu, Tian, Lin: "Immature colon carcinoma transcript-1 promotes cell growth of hepatocellular carcinoma via facilitating cell cycle progression and apoptosis resistance." dans: Oncology reports, Vol. 38, Issue 6, pp. 3489-3496, (2018) (PubMed).

Xie, Zhang, Shen, Cao, Gu, Che: "Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest." dans: OncoTargets and therapy, Vol. 8, pp. 1119-27, (2015) (PubMed).

Détails sur ICT1

Antigène: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Autre désignation: ICT1 (ICT1 Produits)

Synonymes: anticorps ICT1, anticorps DS-1, anticorps DS1, anticorps 1110001A02Rik, anticorps 1110002E03Rik, anticorps mitochondrial ribosomal protein L58, anticorps imitochondrial ribosomal protein L58 S homeolog, anticorps Immature colon carcinoma transcript 1, anticorps MRPL58, anticorps mrpl58.S, anticorps PVX_091510, anticorps mrpl58, anticorps Mrpl58, anticorps ict1

Sujet: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Poids moléculaire: 23630

NCBI Accession: NP_001536

UniProt: Q14197