This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This KCNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the N-terminal region of human KCNB2.
KCNB2
Reactivité: Rat, Souris
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 680
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Cirulli, Kasperaviciūte, Attix, Need, Ge, Gibson, Goldstein: "Common genetic variation and performance on standardized cognitive tests." dans: European journal of human genetics : EJHG, Vol. 18, Issue 7, pp. 815-20, (2010) (PubMed).
Baranzini, Wang, Gibson, Galwey, Naegelin, Barkhof, Radue, Lindberg, Uitdehaag, Johnson, Angelakopoulou, Hall, Richardson, Prinjha, Gass, Geurts, Kragt, Sombekke, Vrenken, Qualley, Lincoln et al.: "Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis...." dans: Human molecular genetics, Vol. 18, Issue 4, pp. 767-78, (2009) (PubMed).
Nyholt, LaForge, Kallela, Alakurtti, Anttila, Färkkilä, Hämaläinen, Kaprio, Kaunisto, Heath, Montgomery, Göbel, Todt, Ferrari, Launer, Frants, Terwindt, de Vries, Verschuren, Brand: "A high-density association screen of 155 ion transport genes for involvement with common migraine." dans: Human molecular genetics, Vol. 17, Issue 21, pp. 3318-31, (2008) (PubMed).
Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." dans: Proteomics, Vol. 7, Issue 11, pp. 1775-85, (2007) (PubMed).
Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." dans: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Antigène
Kv2.2 (KCNB2)
(Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))
anticorps KCNB2, anticorps si:ch211-193n21.1, anticorps Kv2.2, anticorps 9630047L19Rik, anticorps BB130875, anticorps XShab12, anticorps kcnb2, anticorps KV2.2, anticorps potassium voltage-gated channel subfamily B member 2, anticorps potassium voltage-gated channel, Shab-related subfamily, member 2, anticorps potassium channel, voltage gated Shab related subfamily B, member 2, anticorps potassium voltage gated channel, Shab-related subfamily, member 2, anticorps potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog, anticorps KCNB2, anticorps kcnb2, anticorps LOC100051372, anticorps Kcnb2, anticorps kcnb2.S
Sujet
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells.