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KISS1R anticorps (AA 235-263)

KISS1R Reactivité: Humain WB Hôte: Lapin Polyclonal RB40407 unconjugated
N° du produit ABIN1881480
  • Antigène Voir toutes KISS1R Anticorps
    KISS1R (KISS1 Receptor (KISS1R))
    Épitope
    • 12
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 235-263
    Reactivité
    • 51
    • 31
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 1
    Lapin
    Clonalité
    • 59
    • 1
    Polyclonal
    Conjugué
    • 26
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KISS1R est non-conjugé
    Application
    • 25
    • 13
    • 11
    • 10
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.
    Clone
    RB40407
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KISS1R Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    KISS1R (KISS1 Receptor (KISS1R))
    Autre désignation
    KISS1R (KISS1R Produits)
    Synonymes
    anticorps AXOR12, anticorps CPPB1, anticorps GPR54, anticorps HH8, anticorps HOT7T175, anticorps KISS-1R, anticorps Gpr54, anticorps KiSS-1, anticorps gpr54, anticorps gpr54-1, anticorps gpr54a, anticorps kiss1r, anticorps kiss1rl, anticorps kissr2, anticorps si:dkey-31m5.9, anticorps axor12, anticorps kissr1a, anticorps KISS1 receptor, anticorps KISS1 receptor a, anticorps KISS1R, anticorps Kiss1r, anticorps kiss1ra, anticorps kiss1r
    Sujet
    Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
    Poids moléculaire
    42586
    NCBI Accession
    NP_115940
    UniProt
    Q969F8
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