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Keratin 86 anticorps (AA 300-327)

KRT86 Reactivité: Humain WB Hôte: Lapin Polyclonal RB42669 unconjugated
N° du produit ABIN1881488
  • Antigène Voir toutes Keratin 86 (KRT86) Anticorps
    Keratin 86 (KRT86)
    Épitope
    • 6
    • 6
    • 6
    • 6
    AA 300-327
    Reactivité
    Humain
    Hôte
    • 13
    • 1
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Keratin 86 est non-conjugé
    Application
    • 14
    • 13
    • 1
    Western Blotting (WB)
    Homologie
    Sh, B, M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This KRT86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the Central region of human KRT86.
    Clone
    RB42669
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • ZHANG, MENG, ZHAO, TIAN: "Mutation E402K of the hHb6 in a Chinese Han family with monilethrix." dans: European journal of dermatology : EJD, Vol. 19, Issue 5, pp. 508-9, (2009) (PubMed).

    Feng, Liu, Yang: "[Analysis of human hair basic keratin 6 gene mutation in a Chinese Han family with monilethrix]." dans: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 25, Issue 2, pp. 141-4, (2008) (PubMed).

    Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." dans: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

    Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." dans: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).

  • Antigène
    Keratin 86 (KRT86)
    Autre désignation
    KRT86 (KRT86 Produits)
    Synonymes
    anticorps Kb26, anticorps KRT86, anticorps HB6, anticorps Hb1, anticorps KRTHB1, anticorps KRTHB6, anticorps MNX, anticorps hHb6, anticorps 5430421N21Rik, anticorps AI325212, anticorps Khb4, anticorps Krt2-10, anticorps Krt2-11, anticorps MHb4, anticorps keratin 86, anticorps hair keratin type II intermediate filament, anticorps Krt86, anticorps KRT86, anticorps KRT2.11
    Sujet
    The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix.
    Poids moléculaire
    53501
    NCBI Accession
    NP_002275
    UniProt
    O43790
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