Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

LIN7B anticorps (N-Term)

LIN7B Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB40557 unconjugated
N° du produit ABIN1881500
  • Antigène Voir toutes LIN7B Anticorps
    LIN7B (Lin-7 Homolog B (LIN7B))
    Épitope
    AA 35-62, N-Term
    Reactivité
    • 18
    • 9
    • 2
    Humain, Souris
    Hôte
    • 16
    • 2
    • 1
    Lapin
    Clonalité
    • 17
    • 2
    Polyclonal
    Conjugué
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp LIN7B est non-conjugé
    Application
    • 19
    • 15
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Homologie
    B, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This LIN7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human LIN7B.
    Clone
    RB40557
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Zucker, Kama, Kuhn, Thu, Orlando, Dunah, Gokce, Taylor, Lambeck, Friedrich, Lindenberg, Faull, Weiller, Young, Luthi-Carter: "Decreased Lin7b expression in layer 5 pyramidal neurons may contribute to impaired corticostriatal connectivity in huntington disease." dans: Journal of neuropathology and experimental neurology, Vol. 69, Issue 9, pp. 880-95, (2010) (PubMed).

    Sudo, Ito, Iwamoto, Morishita, Asano, Nagata: "Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons." dans: Neuroscience research, Vol. 56, Issue 4, pp. 347-55, (2006) (PubMed).

    Li, Benard, Margolskee: "Ggamma13 interacts with PDZ domain-containing proteins." dans: The Journal of biological chemistry, Vol. 281, Issue 16, pp. 11066-73, (2006) (PubMed).

    Kawai, Fukuda, Mukai, Murata: "MJ0917 in archaeon Methanococcus jannaschii is a novel NADP phosphatase/NAD kinase." dans: The Journal of biological chemistry, Vol. 280, Issue 47, pp. 39200-7, (2005) (PubMed).

  • Antigène
    LIN7B (Lin-7 Homolog B (LIN7B))
    Autre désignation
    LIN7B (LIN7B Produits)
    Synonymes
    anticorps LIN7B, anticorps LIN-7B, anticorps MALS-2, anticorps MALS2, anticorps VELI2, anticorps Veli2, anticorps Veli1a, anticorps lin-7 homolog B, crumbs cell polarity complex component, anticorps lin-7 homolog B (C. elegans), anticorps LIN7B, anticorps Lin7b
    Sujet
    Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ACCN3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity).
    Poids moléculaire
    22896
    NCBI Accession
    NP_071448
    UniProt
    Q9HAP6
    Pathways
    Synaptic Membrane
Vous êtes ici:
Support technique