MET
Reactivité: Humain, Souris, Rat
WB, ELISA, IF, ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Holgren, Dougherty, Edwin, Cerasi, Taylor, Fichera, Joseph, Bissonnette, Khare: "Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: sprouty/c-Met upregulation in human colonic adenocarcinomas." dans: Oncogene, Vol. 29, Issue 38, pp. 5241-53, (2010) (PubMed).
Song, Li, Tretiakova, Salgia, Cagle, Husain: "Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung." dans: Archives of pathology & laboratory medicine, Vol. 134, Issue 11, pp. 1702-5, (2010) (PubMed).
Thanseem, Nakamura, Miyachi, Toyota, Yamada, Tsujii, Tsuchiya, Anitha, Iwayama, Yamada, Hattori, Matsuzaki, Matsumoto, Iwata, Suzuki, Suda, Kawai, Sugihara, Takebayashi, Takei, Ichikawa, Sugiyama et al.: "Further evidence for the role of MET in autism susceptibility. ..." dans: Neuroscience research, Vol. 68, Issue 2, pp. 137-41, (2010) (PubMed).
Sugiura, Kawaguchi, Soejima, Katsumata, Gono, Baba, Kawamoto, Murakawa, Yamanaka, Hara: "Increased HGF and c-Met in muscle tissues of polymyositis and dermatomyositis patients: beneficial roles of HGF in muscle regeneration." dans: Clinical immunology (Orlando, Fla.), Vol. 136, Issue 3, pp. 387-99, (2010) (PubMed).
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.