MMP14 anticorps (C-Term)

N° du produit ABIN1881546

Détail du produit anti-MMP14 anticorps

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Épitope: AA 495-523, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP14 est non-conjugé

Application: Western Blotting (WB)

Homologie: M, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human MMP14.

Clone: RB41662

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-MMP14 (ABIN1881546)

Sakr, Takino, Domoto, Nakano, Wong, Sasaki, Nakanuma, Sato: "GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase." dans: Cancer science, Vol. 101, Issue 11, pp. 2368-74, (2010) (PubMed).

Détails sur MMP14

Antigène: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Autre désignation: MMP14 (MMP14 Produits)

Synonymes: anticorps MMP1, anticorps MMP-14, anticorps MMP-X1, anticorps MT-MMP, anticorps MT-MMP 1, anticorps MT1-MMP, anticorps MT1MMP, anticorps MTMMP1, anticorps mmp-x1, anticorps mt1-mmp, anticorps mtmmp1, anticorps AI325305, anticorps MT-MMP-1, anticorps sabe, anticorps Mt1-mmp, anticorps MT-MMPbeta, anticorps cb386, anticorps sb:cb386, anticorps wu:fb72b09, anticorps mmp14, anticorps matrix metallopeptidase 14, anticorps matrix metallopeptidase 14 (membrane-inserted), anticorps matrix metallopeptidase 14b (membrane-inserted), anticorps matrix metallopeptidase 14a (membrane-inserted), anticorps matrix metallopeptidase 14 L homeolog, anticorps MMP14, anticorps mmp14, anticorps Mmp14, anticorps mmp14b, anticorps mmp14a, anticorps mmp14.L

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Poids moléculaire: 65894

NCBI Accession: NP_004986

UniProt: P50281

Pathways: Autophagy