MMP26 anticorps (AA 96-125)

N° du produit ABIN1881547

Détail du produit anti-MMP26 anticorps

Antigène: MMP26 (Matrix Metallopeptidase 26 (MMP26))

Épitope: AA 96-125

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP26 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.

Clone: RB41665

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-MMP26 (ABIN1881547)

Liu, Cao, Li, Wu, Wang: "GnRH I and II up-regulate MMP-26 expression through the JNK pathway in human cytotrophoblasts." dans: Reproductive biology and endocrinology : RB&E, Vol. 8, pp. 5, (2010) (PubMed).

de Amorim, da Silveira, Queiroz, Galvão, de Souza, de Almeida Freitas: "Matrilysins may not predict the metastatic potential in squamous cell carcinoma of the tongue." dans: Acta odontologica Scandinavica, Vol. 68, Issue 4, pp. 228-31, (2010) (PubMed).

Détails sur MMP26

Antigène: MMP26 (Matrix Metallopeptidase 26 (MMP26))

Autre désignation: MMP26 (MMP26 Produits)

Synonymes: anticorps matrix metallopeptidase 26, anticorps MMP26

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.

Poids moléculaire: 29708

NCBI Accession: NP_068573

UniProt: Q9NRE1