MTAP anticorps (N-Term)

N° du produit ABIN1881557

Détail du produit anti-MTAP anticorps

Antigène: MTAP (Methylthioadenosine phosphorylase (MTAP))

Épitope: AA 8-37, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTAP est non-conjugé

Application: Western Blotting (WB)

Homologie: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human MTAP.

Clone: RB42759

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-MTAP (ABIN1881557)

Newton-Bishop, Chang, Iles, Taylor, Bakker, Chan, Leake, Karpavicius, Haynes, Fitzgibbon, Elliott, Kanetsky, Harland, Barrett, Bishop: "Melanocytic nevi, nevus genes, and melanoma risk in a large case-control study in the United Kingdom." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 8, pp. 2043-54, (2010) (PubMed).

Zhang, Cheng, Yan, Chen, Wang, Yang: "[Association between methylthioadenosine phosphorylase gene single nucleotide polymorphisms and myocardial infarction in Chinese Han ethnicity]." dans: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, Vol. 31, Issue 1, pp. 83-6, (2010) (PubMed).

Huang, Li, Yu, Chou, Tzeng, Hu, Uen, Tian, Wang, Fang, Huang, Wei, Wu, Li: "Homozygous deletion of MTAP gene as a poor prognosticator in gastrointestinal stromal tumors." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 22, pp. 6963-72, (2009) (PubMed).

Détails sur MTAP

Antigène: MTAP (Methylthioadenosine phosphorylase (MTAP))

Autre désignation: MTAP (MTAP Produits)

Synonymes: anticorps BDMF, anticorps DMSFH, anticorps DMSMFH, anticorps LGMBF, anticorps MSAP, anticorps c86fus, anticorps Cc1-6, anticorps 1300019I21Rik, anticorps MTAPase, anticorps zgc:66012, anticorps mtap, anticorps methylthioadenosine phosphorylase, anticorps 5'-methylthioadenosine phosphorylase, anticorps 6-oxopurine nucleoside phosphorylase, anticorps methylthioadenosine phosphorylase L homeolog, anticorps MTAP, anticorps Mtap, anticorps mtaP, anticorps MMAH_RS04260, anticorps TAGG_RS05050, anticorps Toce_0364, anticorps VDIS_RS03165, anticorps MFER_RS02485, anticorps Intca_0886, anticorps DESMU_RS05370, anticorps Dester_1490, anticorps ARCVE_RS05445, anticorps Mahau_1873, anticorps MZHIL_RS01440, anticorps mtap, anticorps mtap.L

Sujet: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

Poids moléculaire: 31236

NCBI Accession: NP_002442

UniProt: Q13126

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process